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Upregulation of p16(INK4A) and Bax in p53 wild/p53-overexpressing crypts in ulcerative colitis-associated tumours

In ulcerative colitis (UC)-associated tumours, p53 gene mutations and p53 protein overexpression are frequently found in early stages, but the two types of alteration do not always coincide. To clarify this discrepancy, p53 mutations and expression of p53-associated molecules were analysed in UC-ass...

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Hlavní autoři: Yoshida, T, Matsumoto, N, Mikami, T, Okayasu, I
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747701/
https://ncbi.nlm.nih.gov/pubmed/15292938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602050
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