A mutant herpes simplex virus type 1 thymidine kinase reporter gene shows improved sensitivity for imaging reporter gene expression with positron emission tomography

We are developing assays for noninvasive, quantitative imaging of reporter genes with positron emission tomography (PET), for application both in animal models and in human gene therapy. We report here a method to improve the detection of lower levels of PET reporter gene expression by utilizing a m...

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Detaylı Bibliyografya

Yayımlandı:	Proc Natl Acad Sci U S A
Asıl Yazarlar:	Gambhir, Sanjiv S., Bauer, Eileen, Black, Margaret E., Liang, Qianwa, Kokoris, Mark S., Barrio, Jorge R., Iyer, Meera, Namavari, Mohammad, Phelps, Michael E., Herschman, Harvey R.
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	National Academy of Sciences 2000
Konular:	Biological Sciences
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16007/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10716999/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.6.2785
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