Detection of inflamed atherosclerotic lesions with diadenosine-5′,5‴-P(1),P(4)-tetraphosphate (Ap(4)A) and positron-emission tomography

Diadenosine-5′,5‴-P(1),P(4)-tetraphosphate (Ap(4)A) and its analog P(2),P(3)-monochloromethylene diadenosine-5′,5‴-P(1),P(4)-tetraphosphate (AppCHClppA) are competitive inhibitors of adenosine diphosphate-induced platelet aggregation, which plays a central role in arterial thrombosis and plaque form...

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Bibliografische gegevens
Hoofdauteurs: Elmaleh, D. R., Fischman, A. J., Tawakol, A., Zhu, A., Shoup, T. M., Hoffmann, U., Brownell, A.-L., Zamecnik, P. C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2006
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1599947/
https://ncbi.nlm.nih.gov/pubmed/17038498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607246103
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