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Direct screening of solution phase combinatorial libraries encoded with externally sensitized photolabile tags

Solution phase combinatorial chemistry holds an enormous promise for modern drug discovery. Much needed are direct methods to assay such libraries for binding of biological targets. An approach to encoding and screening of solution phase libraries has been developed based on the conditional photorel...

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Bibliografiske detaljer
Main Authors: Kottani, Rudresha, Valiulin, Roman A., Kutateladze, Andrei G.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1599888/
https://ncbi.nlm.nih.gov/pubmed/16956977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606380103
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