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In vivo natural killer cell activities revealed by natural killer cell-deficient mice

Studies of natural killer (NK) cell function in vivo have been challenging primarily due to the lack of animal models in which NK cells are genetically and selectively deficient. Here, we describe a transgenic mouse with defective natural killing and selective deficiency in NK1.1(+) CD3(−) cells. De...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Kim, Sungjin, Iizuka, Koho, Aguila, Hector L., Weissman, Irving L., Yokoyama, Wayne M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2000
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15998/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10694580/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.050588297
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