PurF-Independent Phosphoribosyl Amine Formation in yjgF Mutants of Salmonella enterica Utilizes the Tryptophan Biosynthetic Enzyme Complex Anthranilate Synthase-Phosphoribosyltransferase

In Salmonella enterica, the biosynthetic pathways for the generation of purines and the essential cofactor thiamine pyrophosphate branch after sharing five enzymatic steps. Phosphoribosyl amine (PRA) is the first intermediate in the common portion of the pathway and is generated from phosphoribosylp...

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Bibliographic Details
Main Authors: Browne, Beth Ann, Ramos, A. Itzel, Downs, Diana M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Physiology and Metabolism
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1595518/
https://ncbi.nlm.nih.gov/pubmed/16980480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00745-06
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