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The C-Terminal Region of Bacteroides fragilis Toxin Is Essential to Its Biological Activity
To evaluate the role of the C-terminal region in Bacteroides fragilis toxin (BFT) activity, processing, and secretion, sequential C-terminal truncation and point mutations were created by site-directed mutagenesis. Determination of BFT activity on HT29/C1 cells, cleavage of E-cadherin, and the capac...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2006
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1594940/ https://ncbi.nlm.nih.gov/pubmed/16988234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00135-06 |
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