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The C-Terminal Region of Bacteroides fragilis Toxin Is Essential to Its Biological Activity

To evaluate the role of the C-terminal region in Bacteroides fragilis toxin (BFT) activity, processing, and secretion, sequential C-terminal truncation and point mutations were created by site-directed mutagenesis. Determination of BFT activity on HT29/C1 cells, cleavage of E-cadherin, and the capac...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Sears, Cynthia L., Buckwold, Simy L., Shin, Jai W., Franco, Augusto A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2006
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1594940/
https://ncbi.nlm.nih.gov/pubmed/16988234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00135-06
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