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Comparison of Extracellular and Intracellular Potency of Botulinum Neurotoxins

Levels of botulinum neurotoxin (BoNT) proteolytic activity were compared using a cell-free assay and living neurons to measure extracellular and intracellular enzymatic activity. Within the cell-free reaction model, BoNT serotypes A and E (BoNT/A and BoNT/E, respectively) were reversibly inhibited b...

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Detalhes bibliográficos
Main Authors: Cai, Fang, Adrion, Carrie B., Keller, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1594926/
https://ncbi.nlm.nih.gov/pubmed/16988237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00552-06
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