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Gingipains from Porphyromonas gingivalis W83 Synergistically Disrupt Endothelial Cell Adhesion and Can Induce Caspase-Independent Apoptosis

We have shown previously that gingipains from Porphyromonas gingivalis W83 can induce cell detachment, cell adhesion molecule (CAM) cleavage, and apoptosis in endothelial cells; however, the specific roles of the individual gingipains are unclear. Using purified gingipains, we determined that each o...

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Detalhes bibliográficos
Main Authors: Sheets, Shaun M., Potempa, Jan, Travis, James, Fletcher, Hansel M., Casiano, Carlos A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1594922/
https://ncbi.nlm.nih.gov/pubmed/16988242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01140-05
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