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Transcutaneous Immunization with Toxin-Coregulated Pilin A Induces Protective Immunity against Vibrio cholerae O1 El Tor Challenge in Mice
Toxin-coregulated pilin A (TcpA) is the main structural subunit of a type IV bundle-forming pilus of Vibrio cholerae, the cause of cholera. Toxin-coregulated pilus is involved in formation of microcolonies of V. cholerae at the intestinal surface, and strains of V. cholerae deficient in TcpA are att...
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Главные авторы: | , , , , , , , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
American Society for Microbiology
2006
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1594919/ https://ncbi.nlm.nih.gov/pubmed/16988262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00438-06 |
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