Transcutaneous Immunization with Toxin-Coregulated Pilin A Induces Protective Immunity against Vibrio cholerae O1 El Tor Challenge in Mice

Toxin-coregulated pilin A (TcpA) is the main structural subunit of a type IV bundle-forming pilus of Vibrio cholerae, the cause of cholera. Toxin-coregulated pilus is involved in formation of microcolonies of V. cholerae at the intestinal surface, and strains of V. cholerae deficient in TcpA are att...

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Bibliographische Detailangaben
Hauptverfasser: Rollenhagen, Julianne E., Kalsy, Anuj, Cerda, Francisca, John, Manohar, Harris, Jason B., LaRocque, Regina C., Qadri, Firdausi, Calderwood, Stephen B., Taylor, Ronald K., Ryan, Edward T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2006
Schlagworte:
Microbial Immunity and Vaccines
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1594919/
https://ncbi.nlm.nih.gov/pubmed/16988262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00438-06
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