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Porphyromonas gingivalis Fimbriae Proactively Modulate β(2) Integrin Adhesive Activity and Promote Binding to and Internalization by Macrophages
In monocytes, the fimbriae of the oral pathogen Porphyromonas gingivalis activate cross talk signaling from Toll-like receptor 2 (TLR2) to the β(2) integrin CD11b/CD18, leading to the induction of the high-affinity state of the latter receptor. CD14 plays an important role in this “inside-out” proad...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology
2006
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1594907/ https://ncbi.nlm.nih.gov/pubmed/16988241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00784-06 |
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