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Comparison of Protective Efficacy of Subcutaneous versus Intranasal Immunization of Mice with a Brucella melitensis Lipopolysaccharide Subunit Vaccine

Groups of mice were immunized either subcutaneously or intranasally with purified Brucella melitensis lipopolysaccharide (LPS) or with LPS as a noncovalent complex with Neisseria meningitidis group B outer membrane protein (LPS-GBOMP). Control mice were inoculated with sterile saline. Two doses of v...

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Main Authors: Bhattacharjee, Apurba K., Izadjoo, Mina J., Zollinger, Wendell D., Nikolich, Mikeljon P., Hoover, David L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2006
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1594895/
https://ncbi.nlm.nih.gov/pubmed/16988260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00331-06
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