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Different Consequences of ACE2 and SWI5 Gene Disruptions for Virulence of Pathogenic and Nonpathogenic Yeasts

Mutants of Candida albicans, Candida glabrata, and Saccharomyces cerevisiae with disruptions in the ACE2 gene and C. glabrata and S. cerevisiae swi5 disruption mutants were tested for virulence in a murine challenge model of disseminated yeast infection. All mutants showed a clumping phenotype, but...

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Detalhes bibliográficos
Main Authors: MacCallum, Donna M., Findon, Helen, Kenny, Claire C., Butler, Geraldine, Haynes, Ken, Odds, Frank C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1594847/
https://ncbi.nlm.nih.gov/pubmed/16926418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00817-06
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