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Different Consequences of ACE2 and SWI5 Gene Disruptions for Virulence of Pathogenic and Nonpathogenic Yeasts

Mutants of Candida albicans, Candida glabrata, and Saccharomyces cerevisiae with disruptions in the ACE2 gene and C. glabrata and S. cerevisiae swi5 disruption mutants were tested for virulence in a murine challenge model of disseminated yeast infection. All mutants showed a clumping phenotype, but...

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Autors principals: MacCallum, Donna M., Findon, Helen, Kenny, Claire C., Butler, Geraldine, Haynes, Ken, Odds, Frank C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1594847/
https://ncbi.nlm.nih.gov/pubmed/16926418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00817-06
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