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Highly Effective Detection of Human Papillomavirus 16 and 18 DNA by a Testing Algorithm Combining Broad-Spectrum and Type-Specific PCR

The use of a single broad-spectrum human papillomavirus (HPV) DNA-based PCR test may fail to detect lower concentrations of HPV DNA due to competition between different genotypes in mixed infections. To improve HPV detection by PCR, broad-spectrum and type-specific (TS) PCRs were combined, with a fo...

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Autori principali: van Doorn, Leen-Jan, Molijn, Anco, Kleter, Bernhard, Quint, Wim, Colau, Brigitte
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1594708/
https://ncbi.nlm.nih.gov/pubmed/16954263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00539-06
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