Mice with a Targeted Mutation of Patched2 Are Viable but Develop Alopecia and Epidermal Hyperplasia

Hedgehog (Hh) signaling plays pivotal roles in tissue patterning and development in Drosophila melanogaster and vertebrates. The Patched1 (Ptc1) gene, encoding the Hh receptor, is mutated in nevoid basal cell carcinoma syndrome, a human genetic disorder associated with developmental abnormalities an...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Nieuwenhuis, Erica, Motoyama, Jun, Barnfield, Paul C., Yoshikawa, Yoshiaki, Zhang, Xiaoyun, Mo, Rong, Crackower, Michael A., Hui, Chi-chung
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592833/
https://ncbi.nlm.nih.gov/pubmed/16914743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00295-06
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados