Leukemia-Associated, Constitutively Active Mutants of SHP2 Protein Tyrosine Phosphatase Inhibit NF1 Transcriptional Activation by the Interferon Consensus Sequence Binding Protein

Deficiency in either the interferon consensus sequence binding protein (ICSBP) or neurofibromin 1 (Nf1) increases the proliferative response of myeloid progenitor cell to hematopoietic cytokines. Consistent with this, we previously demonstrated that ICSBP activates transcription of the gene encoding...

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Hauptverfasser: Huang, Weiqi, Saberwal, Gurveen, Horvath, Elizabeth, Zhu, Chunliu, Lindsey, Stephan, Eklund, Elizabeth A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2006
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592828/
https://ncbi.nlm.nih.gov/pubmed/16914719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00036-06
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