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New Role for Serum Response Factor in Postnatal Skeletal Muscle Growth and Regeneration via the Interleukin 4 and Insulin-Like Growth Factor 1 Pathways

Serum response factor (SRF) is a crucial transcriptional factor for muscle-specific gene expression. We investigated SRF function in adult skeletal muscles, using mice with a postmitotic myofiber-targeted disruption of the SRF gene. Mutant mice displayed severe skeletal muscle mass reductions due to...

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Autors principals: Charvet, Claude, Houbron, Christophe, Parlakian, Ara, Giordani, Julien, Lahoute, Charlotte, Bertrand, Anne, Sotiropoulos, Athanassia, Renou, Laure, Schmitt, Alain, Melki, Judith, Li, Zhenlin, Daegelen, Dominique, Tuil, David
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592825/
https://ncbi.nlm.nih.gov/pubmed/16914747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00138-06
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