Phosphatidylinositol 3-Phosphate [PtdIns(3)P] Is Generated at the Plasma Membrane by an Inositol Polyphosphate 5-Phosphatase: Endogenous PtdIns(3)P Can Promote GLUT4 Translocation to the Plasma Membrane

Exogenous delivery of carrier-linked phosphatidylinositol 3-phosphate [PtdIns(3)P] to adipocytes promotes the trafficking, but not the insertion, of the glucose transporter GLUT4 into the plasma membrane. However, it is yet to be demonstrated if endogenous PtdIns(3)P regulates GLUT4 trafficking and,...

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Main Authors: Kong, Anne M., Horan, Kristy A., Sriratana, Absorn, Bailey, Charles G., Collyer, Luke J., Nandurkar, Harshal H., Shisheva, Assia, Layton, Meredith J., Rasko, John E. J., Rowe, Tony, Mitchell, Christina A.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592800/
https://ncbi.nlm.nih.gov/pubmed/16880518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00203-06
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