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Forebrain-Specific Inactivation of G(q)/G(11) Family G Proteins Results in Age-Dependent Epilepsy and Impaired Endocannabinoid Formation

Metabotropic receptors coupled to G(q)/G(11) family G proteins critically contribute to nervous system functions by modulating synaptic transmission, often facilitating excitation. We investigated the role of G(q)/G(11) family G proteins in the regulation of neuronal excitability in mice that select...

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Detalhes bibliográficos
Main Authors: Wettschureck, Nina, van der Stelt, Mario, Tsubokawa, Hiroshi, Krestel, Heinz, Moers, Alexandra, Petrosino, Stefania, Schütz, Günther, Di Marzo, Vincenzo, Offermanns, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592765/
https://ncbi.nlm.nih.gov/pubmed/16847339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00397-06
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