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CXCR3 Requires Tyrosine Sulfation for Ligand Binding and a Second Extracellular Loop Arginine Residue for Ligand-Induced Chemotaxis

CXCR3 is a G-protein-coupled seven-transmembrane domain chemokine receptor that plays an important role in effector T-cell and NK cell trafficking. Three gamma interferon-inducible chemokines activate CXCR3: CXCL9 (Mig), CXCL10 (IP-10), and CXCL11 (I-TAC). Here, we identify extracellular domains of...

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Bibliografische gegevens
Hoofdauteurs: Colvin, Richard A., Campanella, Gabriele S. V., Manice, Lindsay A., Luster, Andrew D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2006
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592751/
https://ncbi.nlm.nih.gov/pubmed/16847335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00556-06
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