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Multitasking C(2)H(2) Zinc Fingers Link Zac DNA Binding to Coordinated Regulation of p300-Histone Acetyltransferase Activity

Zac is a C(2)H(2) zinc finger protein that regulates apoptosis and cell cycle arrest through DNA binding and transactivation. The coactivator proteins p300/CBP enhance transactivation through their histone acetyltransferase (HAT) activity by modulating chromatin structure. Here, we show that p300 in...

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Detalhes bibliográficos
Main Authors: Hoffmann, Anke, Barz, Thomas, Spengler, Dietmar
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592709/
https://ncbi.nlm.nih.gov/pubmed/16809786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02270-05
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