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Stabilization of the Retinoblastoma Protein by A-Type Nuclear Lamins Is Required for INK4A-Mediated Cell Cycle Arrest

Mutations in the LMNA gene, which encodes all A-type lamins, including lamin A and lamin C, cause a variety of tissue-specific degenerative diseases termed laminopathies. Little is known about the pathogenesis of these disorders. Previous studies have indicated that A-type lamins interact with the r...

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Main Authors: Nitta, Ryan T., Jameson, Samantha A., Kudlow, Brian A., Conlan, Lindus A., Kennedy, Brian K.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2006
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592700/
https://ncbi.nlm.nih.gov/pubmed/16809772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02464-05
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