Constitutive Hedgehog Signaling in Chondrosarcoma Up-Regulates Tumor Cell Proliferation

Chondrosarcoma is a malignant cartilage tumor that may arise from benign precursor lesions, such as enchondromas. Some cases of multiple enchondromas are caused by a mutation that results in constitutive activation of Hedgehog-mediated signaling. We found that chondrosarcomas expressed high levels o...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Tiet, Tri Dung, Hopyan, Sevan, Nadesan, Puviindran, Gokgoz, Nalan, Poon, Raymond, Lin, Alvin C., Yan, Taiqiang, Andrulis, Irene L., Alman, Benjamin A., Wunder, Jay S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2006
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592680/
https://ncbi.nlm.nih.gov/pubmed/16400033
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars