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Aberrant accumulation of PTTG1 induced by a mutated thyroid hormone β receptor inhibits mitotic progression
Overexpression of pituitary tumor–transforming 1 (PTTG1) is associated with thyroid cancer. We found elevated PTTG1 levels in the thyroid tumors of a mouse model of follicular thyroid carcinoma (TRβ(PV/PV) mice). Here we examined the molecular mechanisms underlying elevated PTTG1 levels and the cont...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1592548/ https://ncbi.nlm.nih.gov/pubmed/17039256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI28598 |
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