Clock mutation affects circadian regulation of circulating blood cells

BACKGROUND: Although the number of circulating immune cells is subject to high-amplitude circadian rhythms, the underlying mechanisms are not fully understood. METHODS: To determine whether intact CLOCK protein is required for the circadian changes in peripheral blood cells, we examined circulating...

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Autors principals: Oishi, Katsutaka, Ohkura, Naoki, Kadota, Koji, Kasamatsu, Manami, Shibusawa, Kentaro, Matsuda, Juzo, Machida, Kazuhiko, Horie, Shuichi, Ishida, Norio
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2006
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592512/
https://ncbi.nlm.nih.gov/pubmed/17014730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1740-3391-4-13
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