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Generation of gene deletions and gene replacements in Escherichia coli O157:H7 using a temperature sensitive allelic exchange system

In this work we describe protocols for the generation of gene deletions and gene replacements using a temperature sensitive plasmid in Escherichia coli O157:H7. This technology requires flanking DNA to be cloned into a temperature sensitive vector but the resulting clone allows great flexibility for...

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Detalles Bibliográficos
Main Authors: Emmerson, James R., Gally, David L., Roe, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado: Biological Procedures Online 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592459/
https://ncbi.nlm.nih.gov/pubmed/17033696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1251/bpo123
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