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Splice Variants of mIAP1 Have an Enhanced Ability to Inhibit Apoptosis
c-IAP1 is a member of the Inhibitor of Apoptosis protein family. Functions ascribed to c-IAP1 include inhibition of apoptosis and activation of NF-κB. Herein, we show that murine c-IAP1 (mIAP1) undergoes alterative splicing, generating two truncated proteins; one that lacks the CARD and RING domains...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1592129/ https://ncbi.nlm.nih.gov/pubmed/16905118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2006.07.176 |
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