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Survivin splice variants are not essential for mitotic progression or inhibition of apoptosis induced by doxorubicin and radiation

Survivin is a critical regulator of mitosis, and an inhibitor of apoptosis which is overexpressed in almost all cancers. In the current study, cell cycle profiles of normal proliferating human umbilical vein endothelial cells, prostate cancer, and lung cancer cell lines expressing varying levels of...

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Detalhes bibliográficos
Main Authors: Jacob, Naduparambil K, Cooley, James V, Shirai, Katsuyuki, Chakravarti, Arnab
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287415/
https://ncbi.nlm.nih.gov/pubmed/22375097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S28147
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