Exposure of cryptic epitopes on transthyretin only in amyloid and in amyloidogenic mutants

The structural requirements for generation of amyloid from the plasma protein transthyretin (TTR) are not known, although it is assumed that TTR is partly misfolded in amyloid. In a search for structural determinants important for amyloid formation, we generated a TTR mutant with high potential to f...

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Dades bibliogràfiques

Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Goldsteins, Gundars, Persson, Håkan, Andersson, Karin, Olofsson, Anders, Dacklin, Ingrid, Edvinsson, Åsa, Saraiva, Maria João, Lundgren, Erik
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1999
Matèries:	Biological Sciences
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15903/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10077645/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.6.3108
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