Inhibition of TNF receptor 1 internalization by adenovirus 14.7K as a novel immune escape mechanism

The adenoviral protein E3-14.7K (14.7K) is an inhibitor of TNF-induced apoptosis, but the molecular mechanism underlying this protective effect has not yet been explained exhaustively. TNF-mediated apoptosis is initiated by ligand-induced recruitment of TNF receptor–associated death domain (TRADD),...

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Autors principals: Schneider-Brachert, Wulf, Tchikov, Vladimir, Merkel, Oliver, Jakob, Marten, Hallas, Cora, Kruse, Marie-Luise, Groitl, Peter, Lehn, Alexander, Hildt, Eberhard, Held-Feindt, Janka, Dobner, Thomas, Kabelitz, Dieter, Krönke, Martin, Schütze, Stefan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2006
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1590267/
https://ncbi.nlm.nih.gov/pubmed/17024246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI23771
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