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The role of receptor internalization in CD95 signaling

Activation of the cell surface CD95 receptor triggers a cascade of signaling events, including assembly of the death-inducing signaling complex (DISC), that culminate in cellular apoptosis. In this study, we demonstrate a general requirement of receptor internalization for CD95 ligand-mediated DISC...

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Detalhes bibliográficos
Main Authors: Lee, Kyeong-Hee, Feig, Christine, Tchikov, Vladimir, Schickel, Robert, Hallas, Cora, Schütze, Stefan, Peter, Marcus E, Chan, Andrew C
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1409734/
https://ncbi.nlm.nih.gov/pubmed/16498403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601016
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