Application of intragenic DNA probes in prenatal screening for retinoblastoma gene carriers in the United Kingdom.

Restriction fragment length polymorphisms (RFLPs) in 55 families affected by retinoblastoma have been studied using recombinant DNA probes derived from within the retinoblastoma predisposition gene. Only six families were uninformative for any of the DNA polymorphisms. The remaining 49 families can...

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Detalhes bibliográficos
Main Authors: Onadim, Z O, Mitchell, C D, Rutland, P C, Buckle, B G, Jay, M, Hungerford, J L, Harper, K, Cowell, J K
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1590195/
https://ncbi.nlm.nih.gov/pubmed/1974756
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