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Mechanisms of oncogenesis in patients with familial retinoblastoma.

In an analysis of mutations in the RB1 gene in three patients, selected at random, who had a positive family history of tumours, we identified mutations, in constitutional cells, involving exons 3, 13 and 17 of the RB1 gene. We used SSCP and PCR sequencing to screen affected individuals and other me...

詳細記述

保存先:
書誌詳細
主要な著者: Onadim, Z., Hogg, A., Cowell, J. K.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 1993
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1968716/
https://ncbi.nlm.nih.gov/pubmed/8217609
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