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A streptococcal protease that degrades CXC chemokines and impairs bacterial clearance from infected tissues

Group A Streptococcus (GAS) causes the life-threatening infection in humans known as necrotizing fasciitis (NF). Infected subcutaneous tissues from an NF patient and mice challenged with the same GAS strain possessed high bacterial loads but a striking paucity of infiltrating polymorphonuclear leuko...

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Detalhes bibliográficos
Main Authors: Hidalgo-Grass, Carlos, Mishalian, Inbal, Dan-Goor, Mary, Belotserkovsky, Ilia, Eran, Yoni, Nizet, Victor, Peled, Amnon, Hanski, Emanuel
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1589981/
https://ncbi.nlm.nih.gov/pubmed/16977314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601327
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