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STEADY-STATE KINETIC MECHANISM OF PDK1

PDK1 catalyzes phosphorylation of Thr in the conserved activation loop region of a number of its downstream AGC kinase family members. In addition to the consensus sequence at the site of phosphorylation, a number of PDK1 substrates contain a PIF sequence (PDK1-Interacting Fragment), which binds and...

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Bibliografische gegevens
Hoofdauteurs: Gao, Xinxin, Harris, Thomas K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2006
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1587617/
https://ncbi.nlm.nih.gov/pubmed/16737971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M602448200
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