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Mitotic recombination map of 13cen–13q14 derived from an investigation of loss of heterozygosity in retinoblastomas

Loss of heterozygosity at tumor-suppressor loci is an important oncogenic mechanism first discovered in retinoblastomas. We explored this phenomenon by examining a set of matched retinoblastoma and leukocyte DNA samples from 158 patients informative for DNA polymorphisms. Loss of heterozygosity at t...

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Detalles Bibliográficos
Main Authors: Hagstrom, Stephanie A., Dryja, Thaddeus P.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC15876/
https://ncbi.nlm.nih.gov/pubmed/10077618
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