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A mutant deubiquitinating enzyme (Ubp-M) associates with mitotic chromosomes and blocks cell division

A new ubiquitin-processing protease (Ubp-M) has been identified in mammalian cells that is phosphorylated at the onset of mitosis and dephosphorylated during the metaphase/anaphase transition. The carboxyl-terminal domain of this 823-aa protein can be phosphorylated in vitro with either extracts of...

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Detalhes bibliográficos
Main Authors: Cai, Shi-Ying, Babbitt, Roger W., Marchesi, Vincent T.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC15854/
https://ncbi.nlm.nih.gov/pubmed/10077596
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