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Yeast flavin-containing monooxygenase generates oxidizing equivalents that control protein folding in the endoplasmic reticulum

The flavin-containing monooxygenase from yeast (yFMO) catalyzes the O(2)- and NADPH-dependent oxidations of biological thiols, including oxidation of glutathione to glutathione disulfide (GSSG). Glutathione and GSSG form the principle redox buffering system in the cell, with the endoplasmic reticulu...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Suh, Jung-Keun, Poulsen, Lawrence L., Ziegler, Daniel M., Robertus, Jon D.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1999
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15830/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10077572/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.6.2687
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