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Yeast flavin-containing monooxygenase generates oxidizing equivalents that control protein folding in the endoplasmic reticulum

The flavin-containing monooxygenase from yeast (yFMO) catalyzes the O(2)- and NADPH-dependent oxidations of biological thiols, including oxidation of glutathione to glutathione disulfide (GSSG). Glutathione and GSSG form the principle redox buffering system in the cell, with the endoplasmic reticulu...

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Autors principals: Suh, Jung-Keun, Poulsen, Lawrence L., Ziegler, Daniel M., Robertus, Jon D.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC15830/
https://ncbi.nlm.nih.gov/pubmed/10077572
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