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Transcriptional activation by artificial recruitment in mammalian cells

We show that the typical “nonclassical” activator, which comprises a fusion protein bearing a component of the transcriptional machinery fused to a DNA-binding domain, activates transcription in mammalian cells only weakly when tested with an array of promoters. However, as found in analogous “artif...

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Autori principali: Nevado, Julián, Gaudreau, Luc, Adam, Maryse, Ptashne, Mark
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC15827/
https://ncbi.nlm.nih.gov/pubmed/10077569
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