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The abundance of the spliceosomal snRNPs is not limiting the splicing of U12-type introns

The rate of excision of U12-type introns has been reported to be slower than that of U2-type introns, suggesting a rate-limiting bottleneck that could down-regulate genes containing U12-type introns. The mechanistic reasons for this slower rate of intron excision are not known, but lower abundance o...

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Detalles Bibliográficos
Main Authors: Pessa, Heli K.J., Ruokolainen, Annukka, Frilander, Mikko J.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1581978/
https://ncbi.nlm.nih.gov/pubmed/16957280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.213906
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