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Structural characteristics of supramolecular assemblies formed by guanidinium-cholesterol reagents for gene transfection

We have recently discovered that cationic cholesterol derivatives characterized by guanidinium polar headgroups are very efficient for gene transfection in vitro and in vivo. In spite of being based on some rationale at the molecular level, the development of these new synthetic vectors was neverthe...

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Autors principals: Pitard, Bruno, Oudrhiri, Noufissa, Vigneron, Jean-Pierre, Hauchecorne, Michelle, Aguerre, Olivier, Toury, Renée, Airiau, Marc, Ramasawmy, Rajen, Scherman, Daniel, Crouzet, Joël, Lehn, Jean-Marie, Lehn, Pierre
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC15818/
https://ncbi.nlm.nih.gov/pubmed/10077560
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