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Inference of population genetic parameters in metagenomics: A clean look at messy data

Metagenomic projects generate short, overlapping fragments of DNA sequence, each deriving from a different individual. We report a new method for inferring the scaled mutation rate, θ = 2N(e)u, and the scaled exponential growth rate, R= N(e)r, from the site-frequency spectrum of these data while acc...

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Bibliographic Details
Main Authors: Johnson, Philip L.F., Slatkin, Montgomery
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1581441/
https://ncbi.nlm.nih.gov/pubmed/16954540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.5431206
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