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A hierarchical approach to protein molecular evolution

Biological diversity has evolved despite the essentially infinite complexity of protein sequence space. We present a hierarchical approach to the efficient searching of this space and quantify the evolutionary potential of our approach with Monte Carlo simulations. These simulations demonstrate that...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Bogarad, Leonard D., Deem, Michael W.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1999
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15812/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10077554/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.6.2591
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