A hierarchical approach to protein molecular evolution
Biological diversity has evolved despite the essentially infinite complexity of protein sequence space. We present a hierarchical approach to the efficient searching of this space and quantify the evolutionary potential of our approach with Monte Carlo simulations. These simulations demonstrate that...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15812/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10077554/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.6.2591 |
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