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Differential effects of PER2 phosphorylation: molecular basis for the human familial advanced sleep phase syndrome (FASPS)

PERIOD (PER) proteins are central components within the mammalian circadian oscillator, and are believed to form a negative feedback complex that inhibits their own transcription at a particular circadian phase. Phosphorylation of PER proteins regulates their stability as well as their subcellular l...

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Detalhes bibliográficos
Main Authors: Vanselow, Katja, Vanselow, Jens T., Westermark, Pål O., Reischl, Silke, Maier, Bert, Korte, Thomas, Herrmann, Andreas, Herzel, Hanspeter, Schlosser, Andreas, Kramer, Achim
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1578693/
https://ncbi.nlm.nih.gov/pubmed/16983144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.397006
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