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A novel histone deacetylase pathway regulates mitosis by modulating Aurora B kinase activity
Histone deacetylase (HDAC) inhibitors perturb the cell cycle and have great potential as anti-cancer agents, but their mechanism of action is not well established. HDACs classically function as repressors of gene expression, tethered to sequence-specific transcription factors. Here we report that HD...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1578679/ https://ncbi.nlm.nih.gov/pubmed/16980585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1455006 |
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